The diterpenes in plant endophytic fungi have novel structure and remarkable biological activity.Among them,12 kinds of skeleton type compounds,such as taxane type,labdane type,harzianone type,isopimarane type,guanacastane type,fusoporin type,indole diterpene type,ginkgolide type,phomactin type,cyclopiane type,norcyclostane type,abietane type,have various biological activities such as anti-tumor,anti-virus,anti-inflammatory,antibacterial and insecticidal.Through sorting out and analyzing relevant literature,a comprehensive review of 137 diterpenoids and their biological activities produced from plant endophytic fungi,and an introduction to some of the biological activity mechanisms and structure-activity relationships,in order to provide a reference for the better development and utilization of plant endophytic fungi diterpenoids.