To investigate the effects of camel blood polypeptide on mitochondrial energy metabolism and free radical metabolism of skeletal muscle in exercise-trained rats.The rats were randomly divided into 6 groups (n=10):control group (C),exercise training group (E),camel blood polypeptide group (P),camel blood polypeptide + exercise training group (PE),taurine group (T),taurine + exercise training group (TE).The E,PE and TE groups were given daily treadmill training,the P and PE groups were gavage with camel blood peptides,and the T and TE groups were gavage with taurine.After 6 weeks,compared with E group,the gastrocnemius GSH-Px activity of PE group was significantly increased (P﹤0.01),while ROS was significantly decreased (P﹤0.01).Camel blood polypeptide combined with exercise training can improve the antioxidant capacity of skeletal muscle and reduce the generation of free radicals,which have better effect than that of exercise training alone.