NATURAL PRODUCT RESEARCH AND DEVELOPMENT ›› 2022, Vol. 34 ›› Issue (3): 491-504. doi: 10.16333/j.1001-6880.2022.3.017

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Advances in chemical constituents and pharmacological activities of lignans from Kadsura coccinea

SUN Ya-hui1,CAO Chun-ya 2,JIN An2*,WU Wei-hua1,2*   

  1. 1School of Pharmacy,Xuzhou Medical University,Xuzhou 221004, China;2 School of Pharmaceutical Sciences,Hunan University of Medicine,Huaihua 418000,China
  • Online:2022-03-28 Published:2022-03-29

Abstract:

Kadsura coccinea is an economic plant with medicinal,edible,ornamental and other values.The research on chemical constituents and pharmacological effects of K. coccinea has achieved rapid progress.More than 200 compounds have been reported so far,including 121 lignans.These lignans have various pharmacological effects,such as anti-inflammatory,anti-tumor,anti-HIV,anti-coagulation,anti-oxidation,liver-protection,ect.The chemical constituents and pharmacological effects of lignans in K. coccinea are reviewed here to provide a reference for the further development and utilization.

Key words: Kadsura coccinea, lignan, chemical constituents, pharmacological activity

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