Talinum paniculatum (Jacp.) Gaertn.is an annual or perennial plant of the Portulacaceae family,which is mainly distributed in central and southern China and is easy to grow.T. paniculatum is an important medicinal and edible homologous plant,which has the functions of removing toxicity for eliminating carbuncles,invigorating spleen-stomach and replenishing qi,unblocking meridians,apromoting lactation and so on.Modern pharmacological studies have found that T. paniculatum contains polysaccharides,flavonoids,phytosterols,alkaloids,triterpenes,organic acids,and possesses pharmacological activities,such as antioxidant,anti-inflammatory and analgesic,antibacterial and heart protection activities.This article mainly describes chemical constituents,pharmacological activities and safety of T. paniculatum,and to provide a reference for further research and development of T. paniculatum.