Arecae Semen is a commonly used Chinese herbal medicine in China,and is listed as the first of the four southern medicines.Areca nut is also a chewing hobby,which has a wide range of pharmacological activities and toxicity.In recent years,domestic and foreign scholars have gradually deepened their research on Arecae Semen.There are many types of chemical components in Arecae Semen,which have a variety of pharmacological effects.Based on the summary of its chemical components,pharmacological effects,toxic effects,clinical applications,and consumption,this paper analyzes the specific chemical components,measurable components,traditional medicinal efficacy,the impact of processing on chemical components The blood components were used to predict and analyze the quality markers of Arecae Semen,and the preferred and alternative components of Arecae Semen quality markers were screened.It provides reference for establishing quality control and evaluation system of Arecae Semen.