Fenghuang Xuecha is a Chinese herbal used for medicinal and dietary purposes,which has great development value.Ultra performance liquid chromatography-quadrupole-time of flight tandem mass spectrometry (UPLC-Q-TOF-MS/MS) coupled with global natural products social molecular networking (GNPS) were used to analysis and identify the chemical components of Fenghuang Xuecha leaves rapidly.The mass spectrometry data were collected by positive and negative ion modes,the chemical components were identified through software analysising,database matching,reference materials comparing and so on,and created the molecular network based on the similarity of the MS/MS fragments.A total of Fifty eight components in Fenghuang Xuecha leaves,the main chemical constituents included 33 flavonoids,11 phenols,four  alkaloids,three triterpenoids and other compounds.Thirty-two compounds were identified for the first time in the genus,such as protocatechuic acid-4-glucoside,myricetin-3-rutinoside,asiatic acid and so on.Meanwhile,the mass fragmentation pattern of each category of compound and the nodes of the flavonoid network correlation analysis were further explored.In this study,LC-MS combined with GNPS could systematic analysis and quickly acquire the ingredients of Fenghuang Xuecha,which will provid reference for its clinical application,quality control and pharmacological material basis.