Simultaneous Extraction of Glabridin and Glycyrrhizic Acid from Glycyrrhiza glabra L.

Abstract

Abstract:

To study the technology of simultaneous extraction of glabridin and glycyrrhizic acid from Glycyrrhiza glabra L., the single factor experiments were done to determine the influencing factors and the orthogonal tests were done to optimize the extracting condition. The extraction conditions were optimized as follows: 60% ethanol containing 0.6% ammonia as extractant, ratio of material to liquid 1:20 (w:v), extraction temperature 75 ℃, and time 2 h. Under these conditions, the extraction rates of Glabridin and Glycyrrhizic acid were 0.238±0.002% and 5.08±0.03% respectively. This technology featured simple operation and yielded the two important bioactive compounds at the same time. The research provided a basis for comprehensive development and utilization of Glycyrrhiza resources with high valued-added.

Key words: Glycyrrhiza glabra L., glabridin, glycyrrhizic acid, extraction

CLC Number:

LI Yu-hui, XU De-ping, ZHANG Lian-fu. Simultaneous Extraction of Glabridin and Glycyrrhizic Acid from Glycyrrhiza glabra L.[J]. NATURAL PRODUCT RESEARCH AND DEVELOPMENT, 2011, 23(3): 547-550.

References 12

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