NATURAL PRODUCT RESEARCH AND DEVELOPMENT ›› 2011, Vol. 23 ›› Issue (4): 655-657.

• Article • Previous Articles     Next Articles

Alkaloids of the Tibetan Medicinal Plant Aconitum naviculare Stapf

HUANG Sheng-zhuo1,3, CAO Jin-xin1,3, JIANG Si-ping2, ZHU Hua-jie1*   

  1. 1State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, China; 2Plateau Institute of Biology, Lhasa 850001, China; 3Graduate School of the Chinese Academy of Sciences, Beijing 100049, China
  • Online:2011-08-25 Published:2011-09-13
  • Supported by:

    This work was funded by the NSFC (30770235), 973 Program (2009CB522300) and Chinese Academy of Sciences (YZ-06-1).

Abstract: Six diterpenoid alkaloids 13-O-acetylhetisine (1), 2-acetyl-13-dehydro-11-epihetisine (2), 2-acetyl-13-dehydro-11-hetisine (3), hetisinone (4), neoline (5), and foresticine (6), together with isoquinoline (7) and dianthrmide (8), were isolated from the Tibetan folk drug Aconitum naviculare. Their structures were elucidated based on 1H and 13C NMR and MS. This is the first report of the presence of compounds 1-8 in this plant.

Key words: Tibetan folk drug, Aconitum naviculare, diterpenoid alkaloids

CLC Number: