Abstract: Marine sediment is a abundant nutrition habitat for microbes. In recent years, a large number of marine streptomyces were isolated from marine sediments, of which some new genera and species were also obtained. Many medicinal active compounds have been found from the marine sediment-derived streptomyces, which promoted the development of marine natural product chemistry and provided the basis for research and development of new drugs. In this paper, types of structures and bioactivities of secondary metabolites produced by marine sediment-derived streptomyces have been briefly reviewed.

Key words: marine sediment, Streptomyces, secondary metabolites, biological activity