Hemostatic Effect of the Node of Lotus Rhizome

NATURAL PRODUCT RESEARCH AND DEVELOPMENT ›› 2011, Vol. 23 ›› Issue (2): 351-355.

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Hemostatic Effect of the Node of Lotus Rhizome

CHEN Ju, ZHANG Jia-li^*

School of Medicine and pharmaceutics, Jiangnan University, Wuxi 214122, China

Received:2009-07-22 Online:2011-04-25 Published:2011-10-14

Abstract

Abstract:

This study investigated the hemostatic effect of ethanol extract and its four different polar fractions from the node of lotus rhizome in vivo by measuring coagulative time (CT), bleeding time (BT), activated partial thromboplastin time (APTT), prothrombin time (PT), thrombin time (TT), euglobulin lysis time (ELT) indexes, etc. The results showed that ethanol extract from the node of lotus rhizome could significantly shorten CT and BT of mice, and the excellent hemostatic effect may be mainly due to the shortening of APTT, PT and prolonging of ELT. Three different dosages of ethyl acetate fraction had the most significant effects on shortening CT, BT, APTT, PT, TT and prolonging ELT, and the next was n-butanol fraction.

Key words: node of lotus rhizome, hemostatic effect, coagulation time, bleeding time, effective fraction

CHEN Ju, ZHANG Jia-Li. Hemostatic Effect of the Node of Lotus Rhizome[J]. NATURAL PRODUCT RESEARCH AND DEVELOPMENT, 2011, 23(2): 351-355.

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Hemostatic Effect of the Node of Lotus Rhizome

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