Antioxidation, Cytotoxicity and α-Glucosidase Inhibition Activities of Asparagus Extract in Vitro

Abstract

Abstract:

The antioxidation，cytotoxicity and α-glucosidase inhibition activities of asparagus extract were investigated in this paper. The antioxidant activity was evaluated by determining the scavenging effects on •DPPH，•OH and nitrite. The cytotoxic activities on human colorectal cancer cells HCT116 and inhibitory effects on α-glucosidase in small intestines of rats were studied. It was found that the scavenging effects on •OH and nitrite was much stronger than that on •DPPH. The results also showed that asparagus extract has α-glucosidase inhibition and cytotoxic activity.

Key words: asparagus extract, free radical, nitrite, α-glucosidase, cytotoxicity

ZHAO Hong-Jun, ZHU Dan, WANG Ke, WANG Rui-Po, LI Jiao, QU Wei-Jing. Antioxidation, Cytotoxicity and α-Glucosidase Inhibition Activities of Asparagus Extract in Vitro[J]. NATURAL PRODUCT RESEARCH AND DEVELOPMENT, 2011, 23(2): 356-360.

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