Chemical Constituents of Lysimachia clethroide Duby

Abstract

Abstract:

Eleven compounds were isolated from the 70% acetone extract of Lysimachia clethroide Duby. On the basis of spectral analysis, they were identified as 23-hydroxyursolic acid (1), isotachioside (2), p-hydroxybenzoic acid (3), 3-methoxy-4-hydroxybenzoic acid (4), 3,4-dihydroxy benzoic acid (5), 3,5-dihydroxybenzoic acid (6), methyl α-D-fructofuranoside (7), uridine (8), β-sitosterol (9), daucosterol (10), and oleanolic acid (11). This is first report of the presence of compounds 1, 2, 4, 7, and 8 in the genus Lysimachia and 3, 5, 6, 9~11 in this plant.

Key words: Lysimachia clethroide Duby, chemical constituents

DING Lin-Fen, MA Yin-Hai, WU Xing-De, GUO Ya-Dong. Chemical Constituents of Lysimachia clethroide Duby[J]. NATURAL PRODUCT RESEARCH AND DEVELOPMENT, 2010, 23(6): 984-986.

References

1 Jiangsu Botanic Institute,Program of Xinhua Herb(新华本草纲要)(Part II),Press of Shanghai Science and Technology,Shanghai,1991,364-371.
2 Xu XY(徐向毅),Tang LH(唐丽华),Liang HQ(梁中琴),et al.Study on anti-tumor effect of the extraction of Lysimachia clethroides Duby.Chin Wild Plant Resour (中国野生植物资源),2003,22(2):31-34.
3 Tang LH(唐丽华),Xu XY(徐向毅),You BG(游本刚).Effect of flavonoids from Lysimachia clethroides on gene expresion of HL-60 cell.Pharmaceutical and Clinical Research (药学与临床研究),2007,15(1):21-24.
4 Tang LH(唐丽华),You BG(游本刚),Xu XY(徐向毅).Effect of flavonoids from Lysimachia clethroides Duby on guide dead of HL-60 cell.Acta Universitatis Traditionis Medicalis Sinensis Pharmacologiaeque Shanghai (上海中医药大学学报),2007,21(1):54-57.
5 Zou HY(邹海艳),Tu PF(屠鹏飞).Study on flavonoids from Lysimachia clethroides.Chin J Nat Med (中国天然药物),2004,2(1):59-61.
6 Ren FZ(任风芝),Qie JK(郄建坤),Qu HH(屈会化),et al.Study on the chemical constituents of Lysimachia clethroides Duby.Pharm J Chin PLA (解放军药学学报),2002,24(2):178-180.
7 Kitagawa I,Matastuda A,Nishimura T,et al.Comparative study on the sapogenin constituents of five primulaceous plan.Chem Pharm Bull,1967,1(59):1435-1437.
8 Tapondjou LA,Lontsi D,Sondengam BL,et al.Saponins from Cussonia bancoensis and their inhibitory effects on nitric oxide production.J Nat Prod.2003,66(9):1266-1269.
9 Inoshiri S,Sasaki M,Kohda H,et al.Aromatic glycosides from Berchemia racemosa.Phytochemistry,1987,26: 2811-2814.
10 Scott KN.Carbon-13 nuclear magnetic resonance of biologically important aromatic acids.I.Chemical shifts of benzoic acid and derivatives.J Am Chem Soc,1972,94:8564-8568.
11 Angyal ST,Bethell GS.Conformational analysis in carbohydrate chemistry.Ⅲ.The 13 C NMR.spectra of the hexuloses.Aust J Chem,1976,29:1249-1265.
12 LI Y(李滢),YANG XW(杨秀伟).Studies on chemical constituents of root tuber of cultivated Pseudostellaria heterophylla (Zheshen No. 1),Chin J Chin Mater Med (中国中药杂志),2008,33(20):2353-2355.

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