Chemical Constituents of Myristica argentea Warb.

NATURAL PRODUCT RESEARCH AND DEVELOPMENT ›› 2010, Vol. 23 ›› Issue (6): 987-990.

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Chemical Constituents of Myristica argentea Warb.

SHI Ji, ZHAO Qi-miao, JIA Tia-zhu^*

Department of Medicines, Liaoning University of Traditional Chinese Medicine, Dalian 116600, China

Received:2009-07-29 Online:2011-01-10 Published:2011-10-19

Abstract

Abstract:

To study the chemical constituents of Myristica argentea, chromatographic and NMR spectroscopic techniques was used to isolate and elucidate the constituents. Twelve compounds were isolated from the whole plant of Myristica argentea by silica gel column and Sephadex LH-20 chromatography and identified as safrole(1), methyleugenol(2), methylisoeugenol(3), 3'-hydroxyisosafrole(4), 7-hydroxy-3',4'-methylene-flavan(5), terephthalic acid dimethyl ester (6), erythro-1,4-di(4-hydroxy-3-methoxyphenyl)-2,3-dimethylbutane (meso-dihydroguaiaretic acid (7), erythro-1-(4-hydroxy-3-methoxyphenyl)-4-(3,4-methylenedioxy phenyl)-2,3-dimethyl butane (8), erythro-1-(4-hydroxy-3-methoxyphenyl)-2-(2-methoxy-4-(1(E)-propenyl)phenoxy)-propan-1-ol (9), nectandrin B(10), β-sitosterol (11), and daucosterol (12). Compounds 4-6 and 8-12 were isolated from this plant for the first time, while compounds 4-6 were isolated firstly from this genus.

SHI Ji, ZHAO Qi-Miao, JIA Tian-Zhu. Chemical Constituents of Myristica argentea Warb.[J]. NATURAL PRODUCT RESEARCH AND DEVELOPMENT, 2010, 23(6): 987-990.

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Chemical Constituents of Myristica argentea Warb.

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