NATURAL PRODUCT RESEARCH AND DEVELOPMENT ›› 2010, Vol. 23 ›› Issue (6): 998-1000.

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Chemical Constituents and Identification of the Caules of Clematis armandii Franch. and Clematis montana Buch.-Ham.

LIU Jing-jing1, 2 , CHEN Xing1* , WEI Zhi-qi, LI Bin1   

  1. 1Sichuan Academy of Chinese Medicine Sciences, Sichuan 610041, China; 2School of Pharmaceutical Sciences, Chengdu University of Traditional Chinese Medicine, Chengdu 611730, China
  • Received:2009-01-20 Online:2011-01-10 Published:2011-10-19

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Abstract:

Four compounds, 9,12-octadecadienoic acid(Z,Z)-,2,3-dihydroxypropyl ester (1), ergosterol (2), stigmasterol (3), and β-sitosterol (4), were isolated from the ethanol extracts of Clematis armandii Franch., and identified on the basis of the spectroscopic and physicochemical data with those reported previously. Compounds 1 and 2 were isolated from the stems of C. armandii for the first time. However, oleanolic acid, an indexed component in Chinese Pharmacopoeia for the identification of Clematis spp. was not detected in our conditions. To determine whether oleanolic acid presented in C. amandii and C. Montana, we collected 11 batch samples include nine for C. amandii and two for C. Montana. There was no trace of oleanolic acid in all 11 samples based on HPLC and TLC analysis, indicating the need for reinvestigation the chemical constituents and the indexed components of C. spp..

Key words: Clematis armandii Franch., Clematis montana Buch.-Ham., ergosterol, stigmasterol, β-sitosterol, identification