NATURAL PRODUCT RESEARCH AND DEVELOPMENT ›› 2014, Vol. 26 ›› Issue (8): 1216-1220.

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Isolation and Characterisation of Enterocins from Marine Streptomyces sp.SCSIO 11863 Isolated from South China Sea

Kumar Saurav, ZHANG Qing-bo, LI Su-mei, ZHANG Wen-jun, TIAN Xin-peng, LI Hui-xian, ZHANG Hai-bo*   

  1. CAS Key Laboratory of Tropical Marine Bio-resources and Ecology,RNAM Center for Marine Microbiology,Guangdong Key Laboratory  of Marine Materia Medica, South China Sea Institute of Oceanology, Chinese Academy of Sciences,Guangzhou 510301 ,China
  • Online:2014-08-30 Published:2014-11-06

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Abstract: An actinomycetes strain SCSIO 11863 with strong antibacterial activity was isolated from marine sediment of the South China Sea.Based on the phenotypic and phylogenetic analysis,the strain was identified as a member of Streptomyces and designated as Streptomyces sp.SCSIO 11863 (KC904267).16S rDNA sequence showed 99% similarity with Streptomyces albogriseolus strain ABRIINW EA1145 (GQ925802).Bioactivity guided extraction with ethyl acetate resulted in the isolation of two analogue compounds.Structures were elucidated with detailed analyses of NMR and MS spectra and identified as Enterocin (1) and 5-deoxyenterocin (2).

Key words: marine sediments of South China Sea, marine actinomycetes, Streptomyces sp.SCSIO 11863, enterocins

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