NATURAL PRODUCT RESEARCH AND DEVELOPMENT ›› 2014, Vol. 26 ›› Issue (6): 856-859.

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Phenolic Compounds from the Heart wood of Dalbergia odorifera T.Chen

WANG Hao1,2, MEI Wen-li2,3, YANG De-lan2, ZHONG Hui-min1, DAI Hao-fu2,3*   

  1. 1  College of Chemistry and Molecular Engineering,Qingdao University of Science and Technology,Qingdao 266042 ,China; 2 Key Laboratory of Biology and Genetic Resources of Tropical Crops,Ministry of Agriculture,Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences; 3 Hainan Key laboratory for research and development of natural products from Li folk medicine,Haikou 571101 ,China
  • Online:2014-06-28 Published:2014-11-12

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Abstract: Ten phenolic compounds were isolated from Dalbergia odoriferae and purified by repeated column chromatography on silica and Sephadex LH-20 gel,and their structures were identified as dalbergin (1), 7-O-methylvestitol (2), syringaresinol (3 ), 3,7-dihydroxy-2′,4′-dimethoxyisoflavanone (4), 3′-hydroxy-8-methoxyvestitol (5), 2′,6-dihydroxy-4′-methoxy-2-arylbenzofuran (6), 3′-O-methylviolanone (7), pinocembrin (8),prunetin (9),mucronulatol (10)by spectral analysis.Among these isolates,compound 1 exhibited inhibitory activities against acetylcholinesterase(AChE),and compounds 2-5 were isolated from this plant for the first time.

Key words: Dalbergia odorifera, flavonoids, AChE inhibitory activities

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