NATURAL PRODUCT RESEARCH AND DEVELOPMENT ›› 2014, Vol. 26 ›› Issue (3): 450-453.

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A New Method Developed for the Extraction and Purification of Resveratrol

XU Yue-can*, MA De-xin   

  1. Hill Pharmaceutical Co.,Ltd.,Hunan Yongzhou 425000,China
  • Online:2014-03-29 Published:2014-12-08

Abstract: In this study,resveratrol was extracted from the fermented giant knotweed.A new resin was applied to purify the extracted solution.The influencing factors of resveratrol extraction and purification results,including enzyme,resin,sample amount used for column chromatography and elution volume were investigated.The optimal conditions were determined to be:enzymolysis of raw material with distiller's yeast for 24 h under 35-40 ℃,extract with 75% ethanol,purify with XC-7 macroporous resin column chromatography,use 10% to 60% ethanol to elute.After concentrating,vacuum drying,the content of resveratrol in product reached 85%.The conversion rate of resveratrol was hence higher than 85%.

Key words: resveratrol, giant knotweed, enzymolysis, macroporous resin

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