Abstract: The caffeoylquinic acid derivatives from the whole plant of Inula cappa were isolated by using a combination of various chromatographic techniques including silica gel chromatography,Sephadex LH-20 chromatography and preparative HPLC.Their structures were identified by their physical-chemical properties and spectroscopic analysis. Eight compounds were isolated and identified as 1,5-di-O-caffeoylquinic acid(1),1,3,5-tri-O-caffeoylquinic acid(2),methyl-3,5-di-O-caffeoyl quinate(3), methyl-3,4-di-O-caffeoylquinate(4),ethyl-3,4-di-O-caffeoylquinate(5),ethyl-4,5-di-O-caffcoylquinate(6),3,5-di-O-caffeoylquinic acid(7), 3,4-di-O-affeoylquinic acid(8).Compounds 1-3 were isolated from this species for the first time.Compounds 4-6 were found from the genus firstly.

Key words: Inula cappa, chemical constituent, caffeoylquinic acid derivative