Abstract: Ten diterpene compounds were isolated from Isodon erioealyx in Guizhou by the comprehensive utilization of silica gel,Sephadex LH-20 and MCI column chromatography.Their structures were identified on the basis of spectrum data and literature.All compounds were elucidated as 6-acetyl-Maoecrystal B (1), Maoecrystal O (2),12-hydroxydehydro-abietic acid (3),Neorabdosin (4),Maoecrystal D (5),Maoecrystal E (6),Maoecrystal B (7),Maoecrystal N (8),Coetsoidin A (9),Maoecrystal L (10),respectively.Compound 1 was a new natural product.Compound 3 was firstly isolated from I.erioealyx.

Key words: Isodon erioealyx, chemical constituents, diterpenes