NATURAL PRODUCT RESEARCH AND DEVELOPMENT ›› 2015, Vol. 27 ›› Issue (2): 232-235. doi: 10.16333/j.1001-6880.2015.02.007

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Carotenoids Production by Rhodotorula rubra JLC under Solid State Fermentation of Waste Tobacco Stems

GUO Da-cheng1, ZHANG Ke-ke2, DONG Gui-bin2, ZHANG Xu-ping2, LIU Hui2, ZHU Da-heng2, XI Yu2*   

  1. 1 Henan Provincial Center for Disease Control and Prevention,Zhengzhou 450016,China; 2 School of Life Science,Zhengzhou University,Zhengzhou 450001,China
  • Online:2015-02-15 Published:2015-02-15

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Abstract: Tobacco stem is a typical solid waste in the tobacco industry,to explore technologies for the resource utilization of waste tobacco stems (WTS),Plackett-Burman (PB) design was employed to evaluate some variables which were relevant to carotenoids production of Rhodotorula rubra JLC under solid state fermentation of WTS.Among ten selected variables,loading capacity,culturing time and yeast powder,as three key factors,were found to significantly influence carotenoids production via PB design and the following statistic analysis.Under PB design conditions,the maximum production of carotenoids reached 21.54 μg/g.

Key words: tobacco stem;solid state fermentation;carotenoids, Plackett-Burman design;Rhodotorula rubra

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