Abstract: In this study,flavonoids from Chrysanthemum morifolium ramat.was extracted by four methods,and finally microwave-assisted extraction method was selected to be used.The parameters of microwave-assisted extraction were optimized by orthogonal experiments.The results showed that the optimal extraction conditions were as follows:40:1 (mL/g) as liquid-solid ratio,120 s as extraction duration and extract 4 times with 20% (w/w) ethanol.Under the optimal conditions,the extraction yield of flavonoids from Chrysanthemum morifolium ramat. was 7.1%.The developed microwave-assisted extraction method was simple,time-saving,efficient and economic for the extraction of flavonoids from Chrysanthemum morifolium ramat.

Key words: Chrysanthemum morifolium ramat., flavonoids, microwave-assisted extraction