Abstract: Sixteen compounds were isolated and purified from EtOAc fraction derived from 95% ethanol extract of Melastoma dodecandrum Lour by silica gel,Sephadex LH-20 and ODS column chromatography.On the basis of their physicochemical properties and spectroscopic data,these compounds were identified as eicosyl-(E)-ferulate (1), oxybenzoic acid (2), vanillic acid (3), p-coumaric acid (4),methyl gallate (5),ethyl gallate (6),protocatechuic acid (7),gallic acid (8),3-O-methylellagic acid (9),3,3′-O-dimethyl ellagic acid 4-O-α-L-rhamnopyranoside (10),4-O-(6″-O-p-coumaroyl-β-D-glucopyranosyl)-p-coumaric acid (11),2-O-(E)-caffeoyl-1-O-p-(E)coumaroyl-β-D-glucopyrannose (12),1,5-di-O-caffeoylquinicacid (13), p-hydroxyacetophenone (14),aviculin (15),xanthienopyran (16).All of these compounds except compound 8 were obtained from Melastoma dodecandrum Lour for the first time.

Key words: Melastoma dodecandrum L, chemical constituents, phenolic acids