Abstract: The aim of this study was to investigate content variation rules of flavonol glucoside and terpene lactones in Ginkgo biloba L.leaves with different growth periods from Yongzhou Hunan using high performance liquid chromatography.The results showed that distinct variations of the contents of flavonol glucoside and terpene lactones took place in the different growth periods of the leaves.The contents of flavonol glucoside and terpene lactones in the leaves reached highest in September.

Key words: Ginkgo biloba L.leaves, flavonol glucoside, terpene lactones, content variation