Abstract: This work investigated the effects of different extraction conditions on the contents and antioxidation of ferulic acid and caffeic acid in Angelica sinensis extracts,the determination of ferulic acid and caffeic acid in Angelica were extracted by HPLC external standard method,the antioxidant activity of Angelica sinensis extracts were detected by DPPH and ABTS.The result showed that the contents of Ferulic acid in different extraction conditions of Angelica sinensis were 0.574-0.707 mg/g and Caffeic acid were 0.012-0.082 mg/g;Angelica sinensis have the highest contents when extracted by alkaline water,and its antioxidant activity is also strongest,but 95% ethanol extraction have the lowest content and weakest antioxidant activity;With the increase of alcohol concentration,The content of Caffeic acid was gradually increased,The content of Ferulic acid increased first and then decreased,Each component has a good synergistic antioxidant effect when extrected by 30%-50% alcohols.

Key words: ferulic acid, caffeic acid, HPLC, DPPH, ABTS, antioxidation